منابع مشابه
Spermatocytes in asun testes arrest during prophase of meiosis I. Arrested asun spermatocytes
asunder is a critical regulator of dynein-dynactin localization during Drosophila spermatogenesis. Michael A. Anderson, Ethan Lee, Karen G. Hales, Tom S. Hays, Laura A. Lee. 1) Dept. of Cell and Developmental Biology, Vanderbilt Univ. Medical Center, Nashville, TN; 2) Dept. of Biology, Davidson College, Davidson, NC; 3) Dept. of Genetics, Cell Biology, and Development, Univ. of Minnesota, Minne...
متن کاملImplementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts
Sexual reproduction is crucially dependent on meiosis, a conserved, specialized cell division programme that is essential for the production of haploid gametes. Here we demonstrate that fertility and the implementation of the meiotic programme require a previously uncharacterized meiosis-specific protein, MEIOC. Meioc invalidation in mice induces early and pleiotropic meiotic defects in males a...
متن کاملThe p27cip/kip ortholog dacapo maintains the Drosophila oocyte in prophase of meiosis I.
Animal oocytes undergo a highly conserved developmental arrest in prophase of meiosis I. Often this marks a period of rapid growth for the oocyte and is necessary to coordinate meiotic progression with the developmental events of oogenesis. In Drosophila, the oocyte develops within a 16-cell germline cyst. Throughout much of oogenesis, the oocyte remains in prophase of meiosis I. By contrast, i...
متن کاملA Wisp3 Cre-knockin Allele Produces Efficient Recombination in Spermatocytes during Early Prophase of Meiosis I
Individuals with the autosomal recessive skeletal disorder Progressive Pseudorheumatoid Dysplasia have loss-of-function mutations in WISP3, and aberrant WISP3 expression has been detected in tumors from patients with colon and breast cancer. In mice however, neither absence nor over-expression of WISP3 was found to cause a phenotype, and endogenous Wisp3 expression has been difficult to detect....
متن کاملProgression through meiosis I and meiosis II in Arabidopsis anthers is regulated by an A-type cyclin predominately expressed in prophase I.
Meiosis is often described as a special case of cell division since it differs from mitosis in having two nuclear divisions without an intervening S-phase. It will be of great interest to uncover what molecular mechanisms underlie these special features of meiosis. We previously reported that the tardy asynchronous meiosis (tam) mutant of Arabidopsis (Arabidopsis thaliana) is slower in cell cyc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell
سال: 2020
ISSN: 0092-8674
DOI: 10.1016/j.cell.2020.04.038